"Immunome Research" in the context of COVID-19

-

                            "Immunome Research" in the context of COVID-19

Coronaviruses are pathogens of humans and animals of agricultural and veterinary importance. Prior to 2003, a number of coronaviruses were known to cause severe diseases in animals, whilst human coronaviruses were typically associated with mild respiratory illnesses. This changed with the zoonotic transmission of the potentially fatal severe acute respiratory syndrome coronavirus (SARS-CoV; in 2003) and Middle East respiratory syndrome coronavirus (MERS-CoV; in 2012) to humans. Moreover, the emergence of swine acute diarrhoea syndrome coronavirus (SADS-CoV; in 2016) and currently, a novel human coronavirus (2019-nCoV) in China, that has resulted in fatalities, highlights the risks of highly pathogenic coronaviruses to human and animal health. Coronavirus pathogenesis is understudied, but must be comprehensively understood if coronavirus infections are to be prevented and managed.

This Special Issue seeks all types of manuscripts (e.g., reviews, research articles, and short communications) on coronavirus-host interactions that lead to highly pathogenic infections of human and animals including: overcoming interspecies barriers to zoonotic transmission, coronavirus evasion of host immune responses, the mechanisms resulting in cellular and tissue damage, and the virus and host genetic determinants underlying pathogenesis and person-to-person/animal-to-animal transmission.

Comments

Post a Comment

Medical Health Sciences

Popular posts from this blog

STUDY OF UGIT (P-14)

-
Image
  14- Obesity An estimated 60 percent of Americans aged 20 years and older are considered overweight and one-quarter are considered obese. Being overweight means that you have an excess amount of body weight, including muscle, bone, fat and water. Being obese means that you have an excess amount of body fat. Obesity significantly increases your risk of developing life-threatening conditions, such as heart disease, stroke, high blood pressure, type 2 diabetes and some forms of cancer. Each year, approximately 280,000 adults die from an obesity-related condition in the United States. Additionally, studies have shown that people who are overweight often suffer from societal discrimination, which may lead to depression, self-esteem and body issue problems. Causes of Obesity Obesity is a complex and chronic disease with many causes. It is not simply a result of overeating. Research has shown that genetics can play a significant role in determining a person's body weight, particula...
Read more

Basic Components of the Immune System

-
Image
INTRODUCTION      It is generally believed that the immune system evolved as the host’s defense against infectious agents, and it is well known that patients with deficiencies in the immune system generally succumb to these infectious diseases. However, as we shall see, it may well play a larger role in the elimination of other foreign substances, including tumor antigens or cells and antibodies that attack self. An immune response may be conveniently divided into two parts:  1) a specific response to a given antigen and  2) a more nonspecific augmentation to that response.       An important feature of the specific response is that there is a quicker response to the antigen during a second exposure to that antigen. It is the memory of the initial response that provides the booster effect. For convenience, the specific immune response may be divided into two parts:  1) the humoral response and  2) ...
Read more

Pulmonary Hypertension

-
Image
WHO Classification of Pulmonary Hypertension Group I. Pulmonary Arterial Hypertension Idiopathic primary Familial and related Disorders collagen vascular disease, congenital systemic to pulmonary shunts, portal hypertension, HIV, drugs and toxins, thyroid disorders, glycogen storage disease, Gaucher’s disease, hereditary hemorrhagic telangiectasia, hemoglobinopa thies, myeloproliferative disorders, splenectomy Associated with Significant Venous or Capillary Involvement pulmonary venoocclusive disease, pulmonary capillary hemangiomatosis Persistent Pulmonary Hypertension of Newborn Group II. Pulmonary venous Hypertension left sided atrial or ventricular heart disease, left sided valvular heart disease Group III. Pulmonary Hypertension associated with Hypoxemia COPD, interstitial lung disease, sleep disordered breathing, alveolar hypoventilation disorders, chronic exposure to high altitude, developmental abnormalities Group IV. Pulmonary Hypertension due to chronic Thromb...
Read more